The full list of publications can be found on Google Scholar .

2025

p53 mutation biases squamocolumnar junction progenitor cells towards dysplasia rather than metaplasia in Barrett's oesophagus. Guodong Lian, Ermanno Malagola, Chengguo Wei, Qiongyu Shi, Junfei Zhao, Masahiro Hata, Hiroki Kobayashi, Yosuke Ochiai, Biyun Zheng, Xiaofei Zhi, Feijing Wu, Ruhong Tu, Osmel Companioni Nápoles, Wenjing Su, Leping Li, Changqing Jing, Man Chen, Leah Zamechek, Richard Friedman, Karol Nowicki-Osuch, Michael Quante, Jianwen Que, Timothy C Wang Gut 2025 Jan 17;74(2):182-196. doi: 10.1136/gutjnl-2024-332095.

2024

Disentangling oncogenic amplicons in esophageal adenocarcinoma. Ng AWT, McClurg DP, Wesley B, Zamani SA, Black E, Miremadi A, Giger O, Hoopen RT, Devonshire G, Redmond AM, Grehan N, Jammula S, Blasko A, Li X, Aparicio S, Tavaré S; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium; Nowicki-Osuch K, Fitzgerald RC. Nat Commun. 2024 May 28;15(1):4533. doi: 10.1038/s41467-024-48912-y.

Dysbiosis of the Upper Gastrointestinal Tract in Head-and-Neck Cancer Survivors: A Pilot Study Using the Capsule Sponge Device. Natalia Zeber-Lubecka, Maria Kulecka, Michalina Dabrowska, Anna Kluska, Magdalena Piątkowska, Maryla Helena Turkot, Nastazja Dagny Pilonis, Aisha Yusuf, Karol Nowicki-Osuch, Michal Mikula, Jerzy Ostrowski Cancers 2024 Oct 18;16(20):3528. doi: 10.3390/cancers16203528

2023

Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia. Nowicki-Osuch K.^, Zhuang L., Cheung T. S., Black E. L., Masqué-Soler N., Devonshire G., Redmond A.M., Freeman A., di Pietro M., Pilonis N., Januszewicz W., O'Donovan M., Tavaré S., Shields J. D., Fitzgerald R. C.^ Cancer Discov. 2023 Jun 2;13(6):1346-1363. doi: 10.1158/2159-8290.CD-22-0824.

2022

Multi-omic cross-sectional cohort study of pre-malignant Barrett's esophagus reveals early structural variation and retrotransposon activity. Katz-Summercorn, A. C.; Jammula, S.; Frangou, A.; Peneva, I.; O'Donovan, M.; Tripathi, M.; Malhotra, S.; Di Pietro, M.; Abbas, S.; Devonshire, G.; Januszewicz, W.;  Blasko, A.; Nowicki-Osuch, K.; MacRae, S.; Northrop, A.; Redmond, A. M.; Wedge, D. C.; Fitzgerald, R. C. Nat Commun 2022, 13 (1), 1407.

2021

Complexities in the role of acetylation dynamics in modifying inducible gene activation parameters. Carrera, S.; O'Donnell, A.; Li, Y.; Nowicki-Osuch, K.; Yang, S. H.; Baker, S. M.; Spiller, D.; Sharrocks, A. D. Nucleic Acids Res 2021, 49 (22), 12744-12756.

Molecular phenotyping reveals the identity of Barrett's esophagus and its malignant transition. Nowicki-Osuch, K.*; Zhuang, L.*; Jammula, S.; Bleaney, C. W.; Mahbubani, K. T.; Devonshire, G.; Katz-Summercorn, A.; Eling, N.; Wilbrey-Clark, A.; Madissoon, E.; Gamble, J.; Di Pietro, M.; O'Donovan, M.; Meyer, K. B.; Saeb-Parsy, K.; Sharrocks, A. D.; Teichmann, S. A.; Marioni, J. C.; Fitzgerald, R. C. Science 2021, 373 (6556), 760-767. *These authors contributed equally to this work.

Tolerance to nascent protein misfolding stress requires fine-tuning of the cAMP/PKA pathway. Kritsiligkou, P.; Nowicki-Osuch, K.; Carter, Z.; Kershaw, C. J.; Creamer, D. R.; Weids, A. J.; Grant, C. M. J Biol Chem 2021, 296, 100690.

2020

The mutREAD method detects mutational signatures from low quantities of cancer DNA. Perner, J.*; Abbas, S*.; Nowicki-Osuch, K.*; Devonshire, G.;Eldridge, M. D.; Tavare, S.; Fitzgerald, R. C. Nat Commun 2020, 11 (1), 3166.

scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation. Madissoon, E.; Wilbrey-Clark, A.; Miragaia, R. J.; Saeb-Parsy, K.; Mahbubani, K. T.; Georgakopoulos, N.; Harding, P.; Polanski, K.; Huang, N.; Nowicki-Osuch, K.; Fitzgerald, R. C.; Loudon, K. W.; Ferdinand, J. R.; Clatworthy, M. R.; Tsingene, A.; van Dongen, S.; Dabrowska, M.; Patel, M.; Stubbington, M. J. T.; Teichmann, S. A.; Stegle, O.; Meyer, K. B. Genome Biol 2020, 21 (1), 1.

2019

How Deep Are the Roots of Barrett's Esophagus? Nowicki-Osuch, K.; Di Pietro, M. Gastroenterology 2019, 156 (6), 1928-1930.

Inflammatory pathways are central to posterior cerebrovascular artery remodelling prior to the onset of congenital hypertension. Walas, D.; Nowicki-Osuch, K.; Alibhai, D.; von Linstow Roloff, E.; Coghill, J.; Waterfall, C.; Paton, J. F. J Cereb Blood Flow Metab 2019, 39 (9), 1803-1817.

2017

EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomas. Nowicki-Osuch, K.; Li, Y.; Challinor, M.; Gerrard, D. T.; Hanley, N. A.; Sharrocks, A. D. PLoS One 2017, 12 (7), e0181902.

* - equal contribution

^ - corresponding authors